Software Resources

All of the software developed in the Kay Lab is made to be used by the greater scientific community, and thus is free for public use. You can find descriptions and download links below. Please cite the appropriate work if you publish any data using these tools, and feel free to reach out with questions or suggestions.

Automated Ligator (Aligator)

Aligator analyzes the sequence of any protein (FASTA format) and ranks the best strategies for synthesizing the protein via solid-phase peptide synthesis (SPPS) and native chemical ligation (NCL). Find a description and installation instructions on our GitHub page using the button below. To cite, please reference our paper by Jacobsen, Erickson & Kay, Bioorg Med Chem 2017.

Protein Amino Acid Composition Analysis (PAACMAN)

A Python tool for analyzing amino acid composition of large sets of proteins (FASTA format), as well as the abundance of specific NCL ligation junctions, pseudoprolines, potential aspartimides, or other di-amino acid sequences of interest. Find a description and installation instructions on our GitHub page using the link below.

Program for Elucidating Phage Trends in Directed Evolution (PEPTIDE)

[description pending]